Two new compounds can block cancer cell’s escape route
Cancer cells are capable of escaping chemotherapy and radiotherapy by activating a signaling pathway that prevents them from dying.
View ArticleRecent advances in the understanding of the role and mechanism of CCAR2 in...
Researchers described the dual role of cell cycle and apoptosis regulator 2 (CCAR2) in cancer progression as a tumor suppressor and promoter.
View ArticleAI model calculates percent necrosis in osteosarcoma patients with 99% accuracy
A research team at Johns Hopkins Medicine has created and trained a machine learning model to calculate percent necrosis (PN) -; or, what percentage of a tumor is "dead" and no longer active -; in...
View ArticleSt. Jude scientists discover potential CAR T cell therapy target for brain...
Findings from St. Jude Children's Research Hospital are moving the field of cancer immunotherapy one step closer to treating brain and solid tumors.
View ArticleCombined application of therapeutic viruses and nanomaterials to...
Using oncolytic viruses (OVs) in combination with nanomaterials as a novel approach to cancer treatment.
View ArticleGenetic mutation in OXR1 gene linked to brain development issues
Study investigates the effects of a loss-of-function mutation in the OXR1 gene on neurodevelopment and cellular functions in the human brain. The research shows that OXR1 deficiency impairs neural...
View ArticleStudy delves into the molecular intricacies of osteosarcoma in elderly patients
In a study published in the journal Genes & Diseases, scientists from Union Hospital, Tongji Medical College, and Huazhong University of Science and Technology delve into the molecular intricacies...
View ArticleResearchers discover new class of compound that targets cancer stem cells
Many cancer therapies, in addition to producing numerous side effects, fail to achieve complete tumour remission, partly due to the presence of cancer stem cells, which are difficult to eradicate.
View ArticleAdvancing osteosarcoma prognosis with AI-assisted tumor cell density analysis
Researchers at Kyushu University have developed and validated a machine-learning model that can accurately evaluate the density of surviving tumor cells after treatment in pathological images of...
View ArticleExpanding research and clinical options for children with cancer
In this interview, Dr. Church, the Molecular and Pediatric Pathologist at Boston Children's Hospital, talks to NewsMedical about their work in pediatric oncology, and the need to expand research and...
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